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CNS-resident classical DCs play a critical role in CNS autoimmune disease

Experimental autoimmune encephalomyelitis (EAE) is an inflammatory demyelinating disease of the central nervous system (CNS), induced by the adoptive transfer of myelin-reactive CD4(+) T cells into naive syngeneic mice. It is widely used as a rodent model of multiple sclerosis (MS). The development...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Giles, David A., Duncker, Patrick C., Wilkinson, Nicole M., Washnock-Schmid, Jesse M., Segal, Benjamin M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264723/
https://ncbi.nlm.nih.gov/pubmed/30226829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI123708
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