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Convenient Synthesis and Biological Evaluation of Modafinil Derivatives: Benzhydrylsulfanyl and Benzhydrylsulfinyl [1,2,3]triazol-4-yl-methyl Esters

Simple synthesis and biological activities of modafinil derivatives are described. The key reactions include condensation of acid and propargyl alcohol, subsequent 1,3-dipolar cycloaddition reaction of alkynes and (3-azido-propyl)cyclohexane or (4-azido-butyl)benzene in the presence of sodium ascorb...

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Dades bibliogràfiques
Publicat a:Molecules
Autors principals: Jung, Jae-Chul, Lee, Yeonju, Son, Jee-Young, Lim, Eunyoung, Jung, Mankil, Oh, Seikwan
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264562/
https://ncbi.nlm.nih.gov/pubmed/22173334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules161210409
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