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Agnostic detection of genomic alterations by holistic DNA structural interrogation
There is an established relationship between primary DNA sequence, secondary and tertiary chromatin structure, and transcriptional activity, suggesting that observed differences in one of these properties may reflect changes in the others. Here, we exploit these relationships to show that variations...
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| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6264503/ https://ncbi.nlm.nih.gov/pubmed/30496256 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208054 |
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