t-Bu(2)SiF-Derivatized D(2)-Receptor Ligands: The First SiFA-Containing Small Molecule Radiotracers for Target-Specific PET-Imaging

The synthesis, radiolabeling and in vitro evaluation of new silicon-fluoride acceptor (SiFA) derivatized D(2)-receptor ligands is reported. The SiFA-technology simplifies the introduction of fluorine-18 into target specific biomolecules for Positron-Emission-Tomography (PET). However, one of the rem...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Iovkova-Berends, Ljuba, Wängler, Carmen, Zöller, Thomas, Höfner, Georg, Wanner, Klaus Theodor, Rensch, Christian, Bartenstein, Peter, Kostikov, Alexey, Schirrmacher, Ralf, Jurkschat, Klaus, Wängler, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264418/
https://ncbi.nlm.nih.gov/pubmed/21892125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16097458
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