Consecutive Three-Component Synthesis of 3-(Hetero)Aryl-1H-pyrazoles with Propynal Diethylacetal as a Three-Carbon Building Block

A novel consecutive three-component synthesis of 3-(hetero)aryl-1H-pyrazoles via room temperature Sonogashira arylation of propynal diethylacetal used as a propargyl aldehyde synthetic equivalent has been disclosed. The final acetal cleavage-cyclocondensation with hydrazine hydrochloride at 80 °C ra...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Molecules
Huvudupphovsmän: Levi, Lucilla, Boersch, Christina, Gers, Charlotte F., Merkul, Eugen, Müller, Thomas J. J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: MDPI 2011
Ämnen:
Communication
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264257/
https://ncbi.nlm.nih.gov/pubmed/22064273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16119340
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk