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Studies on the Synthesis of DMAP Derivatives by Diastereoselective Ugi Reactions

Diastereoselective Ugi reactions of DMAP-based aldehydes with α-amino acids and tert-butyl isocyanide were examined. The reactions of 4-(dimethylamino)-2-pyridine-carboxaldehyde with various α-amino acids afforded 2-substituted DMAP derivatives with low diastereoselectivity. On the contrary, reactio...

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Bibliografske podrobnosti
izdano v:Molecules
Main Authors: Mandai, Hiroki, Irie, Shunsuke, Mitsudo, Koichi, Suga, Seiji
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264237/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16108815
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