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An Expeditious Synthesis of [1,2]Isoxazolidin-5-ones and [1,2]Oxazin-6-ones from Functional Allyl Bromide Derivatives

Reaction of allyl bromide (Z)-1 and (Z)-2 with N-substituted hydroxylamine hydrochlorides in presence of tert-butoxide in tert-butanol at reflux provides a short and effective route to [1,2]isoxazolidin-5-ones 3 and [1,2]oxazin-6-ones 4.

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Beltaïef, Imen, Arfaoui, Aïcha, Amri, Hassen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6264200/
https://ncbi.nlm.nih.gov/pubmed/20657429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15064094
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