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Dynamic control of endogenous metabolism with combinatorial logic circuits

Controlling gene expression during a bioprocess enables real‐time metabolic control, coordinated cellular responses, and staging order‐of‐operations. Achieving this with small molecule inducers is impractical at scale and dynamic circuits are difficult to design. Here, we show that the same set of s...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Moser, Felix, Espah Borujeni, Amin, Ghodasara, Amar N., Cameron, Ewen, Park, Yongjin, Voigt, Christopher A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263354/
https://ncbi.nlm.nih.gov/pubmed/30482789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20188605
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