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Mangiferin, an Anti-HIV-1 Agent Targeting Protease and Effective against Resistant Strains
The anti-HIV-1 activity of mangiferin was evaluated. Mangiferin can inhibit HIV-1(ⅢB) induced syncytium formation at non-cytotoxic concentrations, with a 50% effective concentration (EC(50)) at 16.90 μM and a therapeutic index (TI) above 140. Mangiferin also showed good activities in other laborator...
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| Pubblicato in: | Molecules |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6263262/ https://ncbi.nlm.nih.gov/pubmed/21610656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16054264 |
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