(18)F-Positron Emitting/Trimethine Cyanine-Fluorescent Contrast for Image-Guided Prostate Cancer Management

[Image: see text] [(18/19)F]-4, an anionic GCPII/PSMA inhibitor for image-guided intervention in prostate cancer, is described. [(19)F]-4 is radiolabeled with a radiochemical yield that is ≥27% and a molar activity of 190 ± 50 mCi/μmol in a <1 h, one-step, aqueous isotopic exchange reaction. [(19...

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Dettagli Bibliografici
Pubblicato in:J Med Chem
Autori principali: Kommidi, Harikrishna, Guo, Hua, Nurili, Fuad, Vedvyas, Yogindra, Jin, Moonsoo M., McClure, Timothy D., Ehdaie, Behfar, Sayman, Haluk B., Akin, Oguz, Aras, Omer, Ting, Richard
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263152/
https://ncbi.nlm.nih.gov/pubmed/29676909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.8b00240
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