Selective up-regulation of cannabinoid CB(1) receptor coupling to Go-proteins in suicide victims with mood disorders

Brain endocannabinoid system is proposed to play a role in the pathogenesis of affective disorders. In the present study, we analyzed the functionality of the cannabinoid receptor type 1 (CB(a) receptor) at different transduction levels in prefrontal cortex (PFC) of depressed suicide victims. We exa...

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Detalhes bibliográficos
Publicado no:Biochem Pharmacol
Main Authors: Mato, Susana, Pilar-Cuéllar, Fuencisla, Valdizán, Elsa M., González-Maeso, Javier, Rodríguez-Puertas, Rafael, Meana, Javier, Sallés, Joan, Crespo-Facorro, Benedicto, Pazos, Ángel
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263149/
https://ncbi.nlm.nih.gov/pubmed/30099006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.08.012
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