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Development of dual-drug-loaded stealth nanocarriers for targeted and synergistic anti-lung cancer efficacy

Combination chemotherapy is widely exploited for suppressing drug resistance and achieving synergistic anticancer efficacy in the clinic. In this paper, the nanostructured targeting methotrexate (MTX) plus pemetrexed (PMX) chitosan nanoparticles (CNPs) were developed by modifying methoxy polye (thyl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Deliv
Hauptverfasser: Chen, Juan, Yang, Xiaobing, Huang, Liuqing, Lai, Huixian, Gan, Chuanhai, Luo, Xuetao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263111/
https://ncbi.nlm.nih.gov/pubmed/30472899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2018.1477856
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