Aged mice display altered numbers and phenotype of basophils, and bone marrow-derived basophil activation, with a limited role for aging-associated microbiota

BACKGROUND: The influence of age on basophils is poorly understood, as well as the effect of aging-associated microbiota on basophils. Therefore, we studied the influence of aging and aging-associated microbiota on basophil frequency and phenotype, and differentiation from basophil precursors. RESUL...

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Detalhes bibliográficos
Publicado no:Immun Ageing
Main Authors: van Beek, Adriaan A., Fransen, Floris, Meijer, Ben, de Vos, Paul, Knol, Edward F., Savelkoul, Huub F. J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263040/
https://ncbi.nlm.nih.gov/pubmed/30519273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-018-0135-6
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