Non-Small Cell Lung Cancer Clinical Trials Requiring Biopsies with Biomarker-Specific Results for Enrollment Provide Unique Challenges

BACKGROUND: Clinical trials in lung cancer increasingly require subjects to provide fresh tumor tissue as a prerequisite to enrollment. The effects of this requirement on enrollment rates, enrollment durations, and subject selection have not been fully elucidated. METHODS: We retrospectively reviewe...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Spiegel, Marshall L., Goldman, Jonathan W., Wolf, Brian R., Nameth, Danielle J., Grogan, Tristan R., Lisberg, Aaron E., Wong, Deborah J.L., Ledezma, Blanca, Mendenhall, Melody A., Genshaft, Scott, Gutierrez, Antonio J., Abtin, Fereidoun, Wallace, W. Dean, Adame, Carlos R., McKenzie, Jordan, Abarca, Phillip A., Li, Alice, Strunck, Jennifer L., Famenini, Sina, Carroll, James M., Tucker, D. Andrew, Sauer, Lauren, Moghadam, Nima, Elashoff, David, Abaya, Christina D., Brennan, Meghan B., Garon, Edward B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6263029/
https://ncbi.nlm.nih.gov/pubmed/29125624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.31056
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