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PWP1 promotes nutrient-responsive expression of 5S ribosomal RNA

PWP1 is a chromatin binding protein with an important role in animal growth control downstream of mTOR-mediated nutrient sensing. PWP1 has been shown to control tissue growth by promoting the transcription of 5.8S, 18S and 28S ribosomal RNAs (rRNAs) by RNA polymerase I (Pol I). Concomitantly with Po...

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Detalles Bibliográficos
Publicado en:Biol Open
Autores principales: Liu, Ying, Cerejeira Matos, Rita, Heino, Tapio I., Hietakangas, Ville
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262851/
https://ncbi.nlm.nih.gov/pubmed/30361412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.037911
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