Gene co-expression networks in whole blood implicate multiple interrelated molecular pathways in obese asthma

OBJECTIVE: Asthmatic children who develop obesity through adolescence have poorer disease outcomes compared to those that do not. We aimed to characterize the biology of childhood asthma complicated by adult obesity. METHODS: Gene expression networks are powerful statistical tools for characterizing...

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Veröffentlicht in:Obesity (Silver Spring)
Hauptverfasser: Croteau-Chonka, Damien C., Chen, Zhanghua, Barnes, Kathleen C., Barraza-Villarreal, Albino, Celedón, Juan C., Gauderman, W. James, Gilliland, Frank D., Krishnan, Jerry A., Liu, Andrew H., London, Stephanie J., Martinez, Fernando D., Millstein, Joshua, Naureckas, Edward T., Nicolae, Dan L., White, Steven R., Ober, Carole, Weiss, Scott T., Raby, Benjamin A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262830/
https://ncbi.nlm.nih.gov/pubmed/30358166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.22341
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