Drosophila melanogaster as a function-based high-throughput screening model for antinephrolithiasis agents in kidney stone patients

Kidney stone disease involves the aggregation of stone-forming salts consequent to solute supersaturation in urine. The development of novel therapeutic agents for this predominantly metabolic and biochemical disorder have been hampered by the lack of a practical pre-clinical model amenable to drug...

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Vydáno v:Dis Model Mech
Hlavní autoři: Ali, Sohrab N., Dayarathna, Thamara K., Ali, Aymon N., Osumah, Tijani, Ahmed, Mohamed, Cooper, Tyler T., Power, Nicholas E., Zhang, Dongxing, Kim, Dajung, Kim, Rachel, St. Amant, Andre, Hou, Jinqiang, Tailly, Thomas, Yang, Jun, Luyt, Len, Spagnuolo, Paul A., Burton, Jeremy P., Razvi, Hassan, Leong, Hon S.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Company of Biologists Ltd 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262805/
https://ncbi.nlm.nih.gov/pubmed/30082495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.035873
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