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Enigma proteins regulate YAP mechanotransduction
Human cells can sense mechanical stress acting upon integrin adhesions and respond by sending the YAP (also known as YAP1) and TAZ (also known as WWTR1) transcriptional co-activators to the nucleus to drive TEAD-dependent transcription of target genes. How integrin signaling activates YAP remains un...
Gardado en:
| Publicado en: | J Cell Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Company of Biologists Ltd
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6262774/ https://ncbi.nlm.nih.gov/pubmed/30404826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.221788 |
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