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Modulation of the CCR6-CCL20 Axis: A Potential Therapeutic Target in Inflammation and Cancer

Prototypical functions of the chemokine receptor CCR6 include immune regulation by maneuvering cell chemotaxis and selective delimiting of the pro-inflammatory T(H)17 and regulatory T(reg) subsets during chronic or acute systemic inflammation. Inhibition of CCR6 is proposed to attenuate disease symp...

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Detalhes bibliográficos
Publicado no:Medicina (Kaunas)
Main Authors: Ranasinghe, Ranmali, Eri, Rajaraman
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262638/
https://ncbi.nlm.nih.gov/pubmed/30453514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicina54050088
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