Pilot Production of Mesenchymal Stem/Stromal Freeze-Dried Secretome for Cell-Free Regenerative Nanomedicine: A Validated GMP-Compliant Process

In this paper, a pilot production process for mesenchymal stem/stromal freeze-dried secretome was performed in a validated good manufacturing practice (GMP)-compliant cell factory. Secretome was purified from culture supernatants by ultrafiltration, added to cryoprotectant, lyophilized and character...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Bari, Elia, Perteghella, Sara, Di Silvestre, Dario, Sorlini, Marzio, Catenacci, Laura, Sorrenti, Milena, Marrubini, Giorgio, Rossi, Rossana, Tripodo, Giuseppe, Mauri, Pierluigi, Marazzi, Mario, Torre, Maria Luisa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262564/
https://ncbi.nlm.nih.gov/pubmed/30380806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7110190
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