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Comparative Transcriptomics of Rat and Axolotl After Spinal Cord Injury Dissects Differences and Similarities in Inflammatory and Matrix Remodeling Gene Expression Patterns

Following spinal cord injury in mammals, maladaptive inflammation, and matrix deposition drive tissue scarring and permanent loss of function. In contrast, axolotls regenerate their spinal cord after severe injury fully and without scarring. To explore previously unappreciated molecules and pathways...

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Foilsithe in:Front Neurosci
Main Authors: Tica, Jure, Didangelos, Athanasios
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262295/
https://ncbi.nlm.nih.gov/pubmed/30519154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2018.00808
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