Golgi stress mediates redox imbalance and ferroptosis in human cells

Cytotoxic activities of several Golgi-dispersing compounds including AMF-26/M-COPA, brefeldin A and golgicide A have previously been shown to induce autophagy or apoptosis. Here, we demonstrate that these Golgi disruptors also trigger ferroptosis, a non-apoptotic form of cell death characterized by...

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Gepubliceerd in:Commun Biol
Hoofdauteurs: Alborzinia, Hamed, Ignashkova, Tatiana I., Dejure, Francesca R., Gendarme, Mathieu, Theobald, Jannick, Wölfl, Stefan, Lindemann, Ralph K., Reiling, Jan H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6262011/
https://ncbi.nlm.nih.gov/pubmed/30511023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0212-6
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