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Interaction paths promote module integration and network-level robustness of spliceosome to cascading effects

The functionality of distinct types of protein networks depends on the patterns of protein-protein interactions. A problem to solve is understanding the fragility of protein networks to predict system malfunctioning due to mutations and other errors. Spectral graph theory provides tools to understan...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Guimarães, Paulo R., Pires, Mathias M., Cantor, Maurício, Coltri, Patricia P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261937/
https://ncbi.nlm.nih.gov/pubmed/30487551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35160-6
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