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Kinematic Flexibility Analysis: Hydrogen Bonding Patterns Impart a Spatial Hierarchy of Protein Motion

Elastic network models (ENMs) and constraint-based, topological rigidity analysis are two distinct, coarse-grained approaches to study conformational flexibility of macromolecules. In the two decades since their introduction, both have contributed significantly to insights into protein molecular mec...

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Detalhes bibliográficos
Publicado no:J Chem Inf Model
Main Authors: Budday, Dominik, Leyendecker, Sigrid, van den Bedem, Henry
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261933/
https://ncbi.nlm.nih.gov/pubmed/30240209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jcim.8b00267
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