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A statistical framework for radiation dose estimation with uncertainty quantification from the γ-H2AX assay

Over the last decade, the γ–H2AX focus assay, which exploits the phosphorylation of the H2AX histone following DNA double–strand–breaks, has made considerable progress towards acceptance as a reliable biomarker for exposure to ionizing radiation. While the existing literature has convincingly demons...

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Veröffentlicht in:PLoS One
Hauptverfasser: Einbeck, Jochen, Ainsbury, Elizabeth A., Sales, Rachel, Barnard, Stephen, Kaestle, Felix, Higueras, Manuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261578/
https://ncbi.nlm.nih.gov/pubmed/30485322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207464
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