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Activity of the SPCA1 calcium pump couples sphingomyelin synthesis to sorting of secretory proteins in the trans-Golgi network
How the principal functions of the Golgi apparatus - protein processing, lipid synthesis, and sorting of macromolecules - are integrated to constitute cargo-specific trafficking pathways originating from the trans Golgi network (TGN) is unknown. Here we show that the activity of the Golgi localized...
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| Veröffentlicht in: | Dev Cell |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6261503/ https://ncbi.nlm.nih.gov/pubmed/30393074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2018.10.012 |
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