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Rhinovirus infections change DNA methylation and mRNA expression in children with asthma

Human rhinovirus infection (HRVI) plays an important role in asthma exacerbations and is thought to be involved in asthma development during early childhood. We hypothesized that HRVI causes differential DNA methylation and subsequently differential mRNA expression in epithelial cells of children wi...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Pech, Martin, Weckmann, Markus, König, Inke R., Franke, Andre, Heinsen, Femke-Anouska, Oliver, Brian, Ricklefs, Isabell, Fuchs, Oliver, Rabe, Klaus, Hansen, Gesine, v. Mutius, Erika, Kopp, Matthias V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6261460/
https://ncbi.nlm.nih.gov/pubmed/30485264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205275
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