M2 macrophages promote myofibroblast differentiation of LR-MSCs and are associated with pulmonary fibrogenesis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by the histopathological pattern of usual interstitial pneumonia and is associated with a high mortality rate. Recently, lung resident mesenchymal stem cells (LR-MSCs) have been identified as an important contribu...

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Veröffentlicht in:Cell Commun Signal
Hauptverfasser: Hou, Jiwei, Shi, Jingyan, Chen, Ling, Lv, Zhongyang, Chen, Xiang, Cao, Honghui, Xiang, Zou, Han, Xiaodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260991/
https://ncbi.nlm.nih.gov/pubmed/30470231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-018-0300-8
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