miR-181b/Notch2 overcome chemoresistance by regulating cancer stem cell-like properties in NSCLC

BACKGROUND: Lung cancer stem cells have the ability to self-renew and are resistant to conventional chemotherapy. MicroRNAs (miRNAs) regulate and control the expression and function of many target genes; therefore, miRNA disorders are involved in the pathogenesis of human diseases, such as cancer. H...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Wang, Xiaoyuan, Meng, Qingwei, Qiao, Wenbo, Ma, Ruishuang, Ju, Weiwei, Hu, Jing, Lu, Hailing, Cui, Jianqi, Jin, Zhao, Zhao, Yanbin, Wang, Yan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260863/
https://ncbi.nlm.nih.gov/pubmed/30470250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-1072-1
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