High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections

BACKGROUND: The host response to intruders in the central nervous system (CNS) may be beneficial but could also be harmful and responsible for neurologic symptoms and sequelae in CNS infections. This immune response induces the activation of the kynurenine pathway (KP) with the production of neuroac...

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Dades bibliogràfiques
Publicat a:J Neuroinflammation
Autors principals: Quist-Paulsen, Else, Aukrust, Pål, Kran, Anne-Marte Bakken, Dunlop, Oona, Ormaasen, Vidar, Stiksrud, Birgitte, Midttun, Øivind, Ueland, Thor, Ueland, Per Magne, Mollnes, Tom Eirik, Dyrhol-Riise, Anne Ma
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260858/
https://ncbi.nlm.nih.gov/pubmed/30470234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1366-3
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