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CTGF/CCN2 is an autocrine regulator of cardiac fibrosis

Cardiac fibrosis is a common pathologic consequence of stress insult to the heart and is characterized by abnormal deposition of fibrotic extracellular matrix that compromises cardiac function. Cardiac fibroblasts are key mediators of fibrotic remodeling and are regulated by secreted stress-response...

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Detalles Bibliográficos
Publicado en:J Mol Cell Cardiol
Main Authors: Dorn, Lisa E., Petrosino, Jennifer M., Wright, Patrick, Accornero, Federica
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260782/
https://ncbi.nlm.nih.gov/pubmed/30040954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.07.130
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