The genomics of desmoplastic small round cell tumor reveals the deregulation of genes related to DNA damage response, epithelial–mesenchymal transition, and immune response

BACKGROUND: Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive, and poorly investigated simple sarcoma with a low frequency of genetic deregulation other than an Ewing sarcoma RNA binding protein 1 (EWSR1)-Wilm’s tumor suppressor (WT1) translocation. We used whole-exome sequencing to...

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Detalhes bibliográficos
Publicado no:Cancer Commun (Lond)
Main Authors: Devecchi, Andrea, De Cecco, Loris, Dugo, Matteo, Penso, Donata, Dagrada, Gianpaolo, Brich, Silvia, Stacchiotti, Silvia, Sensi, Marialuisa, Canevari, Silvana, Pilotti, Silvana
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260689/
https://ncbi.nlm.nih.gov/pubmed/30486883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40880-018-0339-3
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