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Synthesis and In Vitro Antibacterial Activity of 7-(3-Amino-6,7-dihydro-2-methyl-2H-pyrazolo[4,3-c] Pyridin-5(4H)-yl)fluoroquinolone Derivatives

A series of novel 7-(3-amino-6,7-dihydro-2-methyl-2H-pyrazolo[4,3-c]pyridin- 5(4H)-yl)fluoroquinolone derivatives were designed, synthesized and characterized by (1)H-NMR, MS and HRMS. These fluoroquinolones were evaluated for their in vitro antibacterial activity against representative Gram-positiv...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Guo, Xin, Liu, Ming Liang, Guo, Hui Yuan, Wang, Yu Cheng, Wang, Ju Xian
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6259631/
https://ncbi.nlm.nih.gov/pubmed/21441865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules16032626
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