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Human MX2/MxB: a Potent Interferon-Induced Postentry Inhibitor of Herpesviruses and HIV-1

Interferons limit viral replication by inducing intracellular restriction factors, such as the GTPase MxB (also designated MX2), which inhibits HIV-1 and, as recently shown, herpesviruses. Inhibition of these viruses occurs at ill-defined steps after viral entry and requires formation of MxB dimers...

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Publicat a:J Virol
Autors principals: Staeheli, Peter, Haller, Otto
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Gem
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258936/
https://ncbi.nlm.nih.gov/pubmed/30258007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00709-18
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