Limited Marginal Utility of Deep Sequencing for HIV Drug Resistance Testing in the Age of Integrase Inhibitors

HIV drug resistance genotyping is a critical tool in the clinical management of HIV infections. Although resistance genotyping has traditionally been conducted using Sanger sequencing, next-generation sequencing (NGS) is emerging as a powerful tool due to its ability to detect low-frequency alleles....

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Principais autores: Dalmat, Ronit R., Makhsous, Negar, Pepper, Gregory G., Magaret, Amalia, Jerome, Keith R., Wald, Anna, Greninger, Alexander L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258839/
https://ncbi.nlm.nih.gov/pubmed/30305383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01443-18
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