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A CRISPR–Cas9-triggered strand displacement amplification method for ultrasensitive DNA detection

Although polymerase chain reaction (PCR) is the most widely used method for DNA amplification, the requirement of thermocycling limits its non-laboratory applications. Isothermal DNA amplification techniques are hence valuable for on-site diagnostic applications in place of traditional PCR. Here we...

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Publicado en:Nat Commun
Main Authors: Zhou, Wenhua, Hu, Li, Ying, Liming, Zhao, Zhen, Chu, Paul K., Yu, Xue-Feng
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258682/
https://ncbi.nlm.nih.gov/pubmed/30479331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07324-5
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