Lassa virus activates myeloid dendritic cells but suppresses their ability to stimulate T cells

Lassa virus (LASV) is responsible for a viral hemorrhagic fever in humans and the death of 3,000 to 5,000 people every year. The immune response to LASV is poorly understood, but type I interferon (IFN-I) and T-cell responses appear to be critical for the host. We studied the response of myeloid den...

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Publicado en:PLoS Pathog
Autores principales: Schaeffer, Justine, Carnec, Xavier, Reynard, Stéphanie, Mateo, Mathieu, Picard, Caroline, Pietrosemoli, Natalia, Dillies, Marie-Agnès, Baize, Sylvain
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258464/
https://ncbi.nlm.nih.gov/pubmed/30419076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007430
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