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FGF-23 and α-Klotho Co-Dependent and Independent Functions

PURPOSE OF REVIEW: This review examines what is known about the FGF-23/α-Klotho co-dependent and independent pathophysiological effects, and whether FGF-23 and/or α-Klotho are potential therapeutic targets. RECENT FINDINGS: FGF-23 is a hormone derived mainly from bone, and α-Klotho is a transmembran...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Curr Opin Nephrol Hypertens
1. Verfasser: Quarles, L. Darryl
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258326/
https://ncbi.nlm.nih.gov/pubmed/30451736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MNH.0000000000000467
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