JMJD6 Licenses ERα-Dependent Enhancer and Coding Gene Activation by Modulating the Recruitment of the CARM1/MED12 Co-activator Complex

Whereas the actions of enhancers in gene transcriptional regulation are well established, roles of JmjC domain-containing proteins in mediating enhancer activation remain poorly understood. Here we report that recruitment of the JmjC domain-containing protein 6 (JMJD6) to estrogen receptor alpha (ER...

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Publicado no:Mol Cell
Main Authors: Gao, Wei-wei, Xiao, Rong-quan, Zhang, Wen-juan, Hu, Yi-ren, Peng, Bing-ling, Li, Wen-juan, He, Yao-hui, Shen, Hai-feng, Ding, Jian-cheng, Huang, Qi-xuan, Ye, Tian-yi, Li, Ying, Liu, Zhi-ying, Ding, Rong, Rosenfeld, Michael G., Liu, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6258263/
https://ncbi.nlm.nih.gov/pubmed/29628309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.03.006
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