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Chiral Syn-1,3-diol Derivatives via a One-Pot Diastereoselective Carboxylation/ Bromocyclization of Homoallylic Alcohols

Chiral syn-1,3-diols are fundamental structural motifs in many natural products and drugs. The traditional Narasaka-Prasad diastereoselective reduction from chiral β-hydroxyketones is an important process for the synthesis of these functionalized syn-1,3-diols, but it is of limited applicability for...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Huang, Guanxin, Liu, Minjie, Xiong, Fangjun, Meng, Ge, Tao, Yuan, Wu, Yan, Peng, Haihui, Chen, Fener
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257933/
https://ncbi.nlm.nih.gov/pubmed/30476789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2018.11.010
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