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Isorhamnetin protects against bleomycin-induced pulmonary fibrosis by inhibiting endoplasmic reticulum stress and epithelial-mesenchymal transition

The present study aimed to determine whether isorhamnetin (Isor), a natural antioxidant polyphenol, has antifibrotic effects in a murine model of bleomycin-induced pulmonary fibrosis. A C57 mouse model of pulmonary fibrosis was established by intraperitoneal injection of a single dose of bleomycin (...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Med
Hauptverfasser: Zheng, Qing, Tong, Ming, Ou, Baiqing, Liu, Cuizhong, Hu, Changping, Yang, Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257865/
https://ncbi.nlm.nih.gov/pubmed/30387812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3965
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