Cargando...

Synthesis of [4-(2-Hydroxyphenyl)thiazol-2-yl]methanones as Potential Bioisosteres of Salicylidene Acylhydrazides

A focused library of [4-(2-hydroxyphenyl)thiazol-2-yl]methanones was prepared in a four-step synthesis with the aim to obtain potent inhibitors of type III secretion in Gram-negative bacteria. The compounds are potential bioisosteres of salicylidene acylhydrazides that are a known class of type III...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Molecules
Main Authors: Hillgren, J. Mikael, Dahlgren, Markus K., To, Tam M., Elofsson, Mikael
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257736/
https://ncbi.nlm.nih.gov/pubmed/20877207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15096019
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!