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Solid-Phase Synthesis of the Lipopeptide Myr-HBVpreS/2-78, a Hepatitis B Virus Entry Inhibitor

Chronic HBV infection is the leading cause of liver cirrhosis and hepatocellular carcinoma (HCC). Synthetic peptides derived from the N-terminus of the large HBV envelope protein (L-protein) have been shown to efficiently block HBV entry. Myr-HBVpreS/2-78, the parent compound of these drugs, inhibit...

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Publicat a:Molecules
Autors principals: Schieck, Alexa, Müller, Thomas, Schulze, Andreas, Haberkorn, Uwe, Urban, Stephan, Mier, Walter
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6257642/
https://ncbi.nlm.nih.gov/pubmed/20657392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15074773
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