In Vitro and in Vivo Effects of Three Different Mitragyna speciosa Korth Leaf Extracts on Phase II Drug Metabolizing Enzymes—Glutathione Transferases (GSTs)

In the present study, we investigate the effects of three different Mitragyna speciosa extracts, namely methanolic, aqueous and total alkaloid extracts, on glutathione transferase-specific activity in male Sprague Dawley rat liver cytosol in vitro and in vivo. In the in vitro study, the effect of Mi...

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Veröffentlicht in:Molecules
Hauptverfasser: Azizi, Juzaili, Ismail, Sabariah, Mordi, Mohd Nizam, Ramanathan, Surash, Said, Mohd Ikram Mohd, Mansor, Sharif Mahsufi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Molecular Diversity Preservation International 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256986/
https://ncbi.nlm.nih.gov/pubmed/20110902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules15010432
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