Differential roles of p38 MAPK and ERK1/2 in angiopoietin-2-mediated rat pulmonary microvascular endothelial cell apoptosis induced by lipopolysaccharide

Angiopoietin-2 (Ang-2) is a Tie-2 ligand that destabilizes vascular structures, enhances vascular permeability and induces vascular regression and endothelial cell apoptosis. Although there is evidence for the involvement of the Ang/Tie2 axis in acute lung injury (ALI), the underlying mechanisms inv...

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Vydáno v:Exp Ther Med
Hlavní autoři: Li, Shi, Zhong, Mingmei, Yuan, Yuan, Zhang, Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2018
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256857/
https://ncbi.nlm.nih.gov/pubmed/30546397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.6810
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