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Synthesis, characterization and biological activity of organometallic derivatives of the antimalarial drug mefloquine as new antischistosomal drug candidates

We present the design, synthesis, characterization and biological evaluation of new ferrocenyl and ruthenocenyl derivatives of the organic antimalarial mefloquine, a drug also known for its antischistosomal activity. The two metallocenyl derivatives prepared (3 and 4) demonstrated comparable activit...

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Bibliografiske detaljer
Udgivet i:Medchemcomm
Main Authors: d'Orchymont, Faustine, Hess, Jeannine, Panic, Gordana, Jakubaszek, Marta, Gemperle, Lea, Keiser, Jennifer, Gasser, Gilles
Format: Artigo
Sprog:Inglês
Udgivet: Royal Society of Chemistry 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256353/
https://ncbi.nlm.nih.gov/pubmed/30568758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00396c
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