Thymidine phosphorylase affects clinical outcome following surgery and mRNA expression levels of four key enzymes for 5-fluorouracil metabolism in patients with stage I and II non-small cell lung cancer

The expression levels of thymidine phosphorylase (TP), dihydropyrimidine dehydrogenase (DPD), thymidylate synthase (TS) and orotate phosphoribosyltransferase (OPRT) may predict the clinical efficacy of 5-fluorouracil-based chemotherapy in patients with cancer. We herein investigated the differences...

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Dettagli Bibliografici
Pubblicato in:Mol Clin Oncol
Autori principali: Himuro, Naoya, Niiya, Yumiko, Minakata, Takao, Oshima, Yutaka, Kataoka, Daisuke, Yamamoto, Shigeru, Suzuki, Takashi, Kadokura, Mitsutaka
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2018
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256090/
https://ncbi.nlm.nih.gov/pubmed/30546894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2018.1726
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