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RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation

RANKL signaling is essential for osteoclastogenesis. Its role in osteoblastic differentiation and bone formation is unknown. Here we demonstrate that RANK is expressed at an early stage of bone marrow mesenchymal stem cells (BMSCs) during osteogenic differentiation in both mice and human and decreas...

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Bibliografski detalji
Izdano u:Bone Res
Glavni autori: Chen, Xiao, Zhi, Xin, Wang, Jun, Su, Jiacan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255918/
https://ncbi.nlm.nih.gov/pubmed/30510839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-018-0035-6
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