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RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation
RANKL signaling is essential for osteoclastogenesis. Its role in osteoblastic differentiation and bone formation is unknown. Here we demonstrate that RANK is expressed at an early stage of bone marrow mesenchymal stem cells (BMSCs) during osteogenic differentiation in both mice and human and decreas...
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Publicado no: | Bone Res |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6255918/ https://ncbi.nlm.nih.gov/pubmed/30510839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-018-0035-6 |
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