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Clofazimine, but Not Isoniazid or Rifampicin, Augments Platelet Activation in vitro

Although the inclusion of the cationic amphiphilic, anti-mycobacterial agent, clofazimine, in the chemotherapeutic regimens of patients with multidrug-resistant tuberculosis (TB) has contributed to improved outcomes, concerns remain about the cardiotoxic potential of this agent. Accordingly, the cur...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Anderson, Ronald, Theron, Annette J., Nel, Jan G., Durandt, Chrisna, Cholo, Moloko C., Feldman, Charles, Tintinger, Gregory R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255828/
https://ncbi.nlm.nih.gov/pubmed/30515097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01335
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