543. An Integrated Safety Analysis Comparing Once-Daily Doravirine (DOR) to Darunavir+Ritonavir (DRV+r) and Efavirenz (EFV) in HIV-1-Infected, Antiretroviral Therapy (ART)-Naïve Adults

BACKGROUND: DOR is a novel NNRTI that has shown noninferior efficacy to DRV+r- and EFV-based regimens in phase 3 trials (DRIVE-FORWARD [NCT02275780] and DRIVE-AHEAD [NCT02403674]). A prespecified integrated analysis of those trials plus a completed phase 2 trial (P007; NCT01632345) was performed to...

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Publicado no:Open Forum Infect Dis
Main Authors: Thompson, Melanie, Orkin, Chloe, Molina, Jean-Michel, Gatell, Jose, Sax, Paul, Cahn, Pedro, Squires, Kathleen, Zhou, Yan, Xu, Xia, Rodgers, Anthony, Kumar, Sushma, Teppler, Hedy, Martin, Elizabeth, Hanna, George, Hwang, Carey
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6255676/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofy210.551
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